Iurie Dondiuc
State University of Medicine and Pharmacy, Republic of Moldova
Abstract Title: Complications Associated with Umbilical Cord Abnormalities
Biography:
Iurie Dondiuc, PhD in Medical Sciences, is an Associate Professor at the Department of Obstetrics and Gynecology, Nicolae Testemițanu State University of Medicine and Pharmacy, Republic of Moldova. Over three decades, has made significant contributions to maternal-fetal medicine, perinatology, and reproductive health, participating in the development of national clinical guidelines and health policies. President of the Moldovan Society for Cervical Pathology and Colposcopy and Chairman of the Obstetrics and Gynecology Commission at the Ministry of Health of the Republic of Moldova. Researcher and doctoral supervisor, has published over 150 scientific papers. Expertise: healthcare management & quality improvement, prenatal care strategies.
Research Interest:
This study, conducted at the Nicolae Testemițanu State University of Medicine and Pharmacy, examines the impact of umbilical cord abnormalities on perinatal outcomes. A prospective cohort study was conducted on 190 pregnant women, divided into two groups: L1: 95 women with umbilical cord abnormalities, including single umbilical artery, hypercoiling, hypocoiling, velamentous insertion, and true knots; L2: 95 women with normal umbilical cord morphology. The mean maternal age was comparable between groups (29.09±4.85 years in L1 vs. 27.86±4.36 years in L2, p>0.05), with a coefficient of variation of 15.66% for L2 and 16.66% for L1. Socioeconomic status did not show statistically significant differences between the groups (p>0.05). Key findings indicate that umbilical cord abnormalities significantly increased the risk of: preterm labor (p=0.03); fetal growth restriction (p=0.01); oligohydramnios (p=0.02). Additionally, the L1 group demonstrated higher rates of: acute fetal hypoxia (p=0.04); emergency cesarean sections (p=0.001); lower Apgar scores (p=0.01). Regarding delivery outcomes, vaginal delivery remained predominant in both groups (85.26% in L2 vs. 74.73% in L1), but cesarean sections were significantly more frequent in the L1 group (25.26% vs. 14.74% in L2). Emergency cesarean sections were markedly higher in L1 (11.58% vs. 2.11% in L2, p=0.04). This study underscores the importance of early diagnosis and continuous fetal monitoring to optimize perinatal outcomes in pregnancies complicated by umbilical cord abnormalities.